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The embolus may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs.Clexane is used for prevention of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE) in patients undergoing hip or knee replacement surgery or abdominal surgery; in conjunction with warfarin for inpatient treatment of acute DVT with or without PE, or outpatient treatment of acute DVT without PE. The clotting process is complicated and begins when blood cells called platelets clump together and produce chemicals that activate the clotting process.If using Clexane with peparations which influence hemostasis it is possible development of hemorrhagic complications. The preparation cannot be mixed with other solutions in one syringe. The final part of this process involves a substance called thrombin being activated to produce a protein called fibrin. It can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. Sometimes, however, a blood clot can form abnormally within the blood vessels. Clexane contains the active ingredient Enoxaparin, which is a type of medicine called a low molecular weight heparin. This is the body's natural way of repairing itself. This is known as a thromboembolism.Possible side effects arenosebleeds, bruising, coughing up or vomiting blood, blood in your urineor black, tarry or bloodstained stools, pain and irritation. The medicine must not be used intramuscularly. It stops blood clots forming inside the blood vessels.Clexane causes higher anti-factor Xa to antithrombin activities (anti-factor IIa) ratio than heparin, which may prevent thrombosis.Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. This is known as a thrombus.Hypersensitivity to enoxaparin, heparin, benzyl alcohol, or pork products;Active major bleeding;Thrombocytopenia associated with positive in vitro test for antiplatelet antibody in presence of Enoxaparin. If uses of such combination cannot be avoided, Enoxaparin has to be applyed under the careful control over parameters of blood coagulability. Fibrin binds the platelets together, forming a blood clot.
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